Will my anticoagulants interact with other medications?

Yes, anticoagulants can have issues with other medications. Check with your doctor before getting prescribed anything like NSAID. Xarelto and Eliquis can react with certain seizure medicines, HIV medicines, anti-fungal medications, and TB medicines. There are very few other interactions. However, you should not take Xarelto with Paxlovid since it has an HIV medicine Ritonavir.  With Apixaban you should use half dose. warfarin (Coumadin) has many interactions, which is a good reason to use DOACs if you can for blood clots involving the legs and lungs.