NBCA Video Series – Everything You Ever Wanted to Know About Blood Clotting

Mark T. Reding, M.D., Assistant Professor of Medicine, Director, Center for Bleeding and Clotting Disorders, University of Minnesota

Dr. Mark Reding presents “Everything You Ever Wanted to Know About Blood Clotting”. This presentation has been edited into 8 short segments. Click on the player to view or visit our YouTube Channel by clicking here. Now available on iTunes, click here to download to your iPhone or iPod.

Part 1 of 8

The National Blood Clot Alliance Stop The Clot Forum. Guest speaker Mark T. Reding, M.D., Assistant Professor of Medicine, Division of Hematology, Oncology, & Transplantation Director, Center for Bleeding and Clotting Disorders, University of Minnesota This segment defines: Hemostasis = normal blood clotting, Thrombosis = excessive blood clotting, Thrombophilia = predisposition to thrombosis, DVT = deep vein thrombosis (clot in leg), PE = pulmonary embolus (clot in lung), VTE- venous thromboembolism (DVTs and PEs),

Part 2 of 8

Hemostasis, Thrombosis, How Blood Clots, Primary Hemostasis, Secondary Hemostasis, Hemostasis Stops, Fibrinolysis, Fibrin, Platelet Plug, Platelet activation, Thrombin generation, Regulation of clot formation (Slides 4 – 7)

Part 3 of 8

What happens when we have too much hemostasis? Arterial Thrombosis, Venous Thromboembolism, Epidemiology of Arterial Thrombosis, Stroke, Heart Attack, Epidemiology of VTE, facts and figures (Slides 8 – 10).

Part 4 of 8

Artery and Vein differences regarding clots, Arterial Clots, Venous clots, Superficial Thrombophlebitis, Deep Vein Thrombosis. Pulmonary Embolism, Vascular Structure, Thrombotic Mechanisms and Risk Factors, Treatment (Slides 11 – 15)

Part 5 of 8

Venous Thromboembolism, Genetic Predisposition, Acquired Trigger(s), Thrombosis, family history of blood clotting, genetic thrombophilia, Factor V Leiden, Prothrombin Gene Mutation, Protein C deficiency, Protein S deficiency, Antithrombin-III deficiency, Dysfibrinogenemia,Autosomal dominant inheritance (Slides 16 – 20).

Part 6 of 8

“Thrombosis threshold” “Risk of Thrombosis”

Part 7 of 8

How to Prevent Blood Clots, Mechanical prophylaxis, Pharmacologic prophylaxis, Know the risk factors, Know your family history, Know the symptoms of DVT and PE, Stay active, maintain healthy weight, Early ambulation after surgery, Compression stockings, Pneumatic compression devices, blood thinners, D-dimer, Non-Invasive Imaging, Compression ultrasound, V/Q scan, CT scan, Invasive Imaging, Venography, Pulmonary angiography, DVT: Clinical Findings, PE: Clinical Findings, Diagnosis of VTE, (Slides 26 – 35). NBCA Stop The Clot Forum.

Part 8 of 8

Treatment of Arterial Clots, Risk Factor Modification, Anti-Platelet Medications, Treatment of Venous Clots, Prophylaxis at times of increased risk, Initial / Short-term treatment, Heparin, Low MW Heparin, enoxaparin (Lovenox), dalteparin (Fragmin), Factor Xa Inhibitor, fondaparinux (Arixtra), Long-term treatment, warfarin, Coumadin, Jantoven (Slides 40 – 43)

Other Installments in the Series Include:

Visit NBCA’s YouTube Channel. Click here.

The video production for these programs was done by REM Video & Event Company, St. Louis Park, Minnesota.